  {"id":51283,"date":"2025-09-02T13:26:37","date_gmt":"2025-09-02T17:26:37","guid":{"rendered":"https:\/\/umaine.edu\/research\/?p=51283"},"modified":"2025-09-04T12:45:26","modified_gmt":"2025-09-04T16:45:26","slug":"umaine-amplifies-biomedical-research-with-expanded-zebrafish-lab","status":"publish","type":"post","link":"https:\/\/umaine.edu\/research\/2025\/09\/02\/umaine-amplifies-biomedical-research-with-expanded-zebrafish-lab\/","title":{"rendered":"91福利 amplifies biomedical research with expanded zebrafish lab"},"content":{"rendered":"\n<p>91福利 unveiled an expanded and renovated zebrafish laboratory in Hitchner Hall this July. The facility, jointly funded by two grants from the National Institutes of Health (NIH) totaling $650,000 with additional investment by 91福利, significantly expands the university\u2019s capacity for biomedical research using zebrafish.<\/p>\n\n\n\n<p>Zebrafish have genomes and immune systems similar to humans, making them ideal models for studying genetic, developmental and toxicological variables. The paperclip-sized minnows are prolific and mature quickly. Their more unusual attributes, like having transparent skin as embryos, have made them mainstays in research labs for over a century. 91福利 is a <a href=\"https:\/\/umaine.edu\/news\/blog\/2022\/10\/25\/the-university-of-maines-zebrafish-facility-is-a-hidden-bastion-of-research\/\">well-established leader<\/a> in zebrafish research, being among the first institutions in New England to utilize them as research models and founding the Pine Tree State\u2019s first lab.&nbsp;<\/p>\n\n\n\n<p>\u201cWith this expanded lab, we can speed up experiments, support more rising researchers and train more students,\u201d said Clarissa Henry, professor of biological sciences at 91福利, who secured the grant. \u201cThe renovation addresses the bottlenecks we\u2019ve faced for years, like limited spawning space, and opens the door to new experimental designs and collaborations.\u201d<\/p>\n\n\n\n<p>The new lab space, which repurposed a former teaching space in Hitchner Hall, doubles the square footage of 91福利\u2019s zebrafish research labs. The updated lab is adjacent to existing zebrafish rooms, facilitating seamless integration with current operations. The lab previously served more than a dozen faculty members, along with their technicians, graduate students and undergraduates, like recent University of Maine at Machias alum <a href=\"https:\/\/umaine.edu\/news\/blog\/2025\/07\/16\/lillian-warwick-finding-success-in-opportunities-close-to-coast\/\">Lillian Warwick<\/a>. Now, it has room to grow as zebrafish biomedical research rises in prominence. Since 2007, zebrafish research has accounted for nearly a third of all NIH funding received by the university.&nbsp;<\/p>\n\n\n<style>.kb-image51283_bd2221-b9.kb-image-is-ratio-size, .kb-image51283_bd2221-b9 .kb-image-is-ratio-size{max-width:400px;width:100%;}.wp-block-kadence-column > .kt-inside-inner-col > .kb-image51283_bd2221-b9.kb-image-is-ratio-size, .wp-block-kadence-column > .kt-inside-inner-col > .kb-image51283_bd2221-b9 .kb-image-is-ratio-size{align-self:unset;}.kb-image51283_bd2221-b9 figure{max-width:400px;}.kb-image51283_bd2221-b9 .image-is-svg, .kb-image51283_bd2221-b9 .image-is-svg img{width:100%;}.kb-image51283_bd2221-b9 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<div class=\"wp-block-kadence-image kb-image51283_bd2221-b9\"><figure class=\"alignright size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"683\" height=\"1024\" src=\"https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-683x1024.jpg\" alt=\"Zebrafish in a tank at the University of Maine\" class=\"kb-img wp-image-51286\" srcset=\"https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-683x1024.jpg 683w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-200x300.jpg 200w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-768x1152.jpg 768w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-1024x1536.jpg 1024w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-1365x2048.jpg 1365w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-93x140.jpg 93w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-317x476.jpg 317w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-423x635.jpg 423w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-634x951.jpg 634w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-846x1269.jpg 846w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-951x1427.jpg 951w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653-1268x1902.jpg 1268w, https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/060322_AK_DSC_9653.jpg 1600w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,683px\" \/><\/figure><\/div>\n\n\n\n<p>The upgrades allow researchers to rear more zebrafish in their ideal conditions with better precision, which, in turn, accelerates experiments focused on studying muscular dystrophy, cancer, infections, toxins and other human health challenges. The lab\u2019s expansion is part of a NIH Centers of Biomedical Research Excellence (COBRE) grant that bolstered 91福利\u2019s role as the academic leader for biomedical research in the Pine Tree State and aims to fuel Maine\u2019s growing biotech sector.<\/p>\n\n\n\n<p>\u201cThe new spawning shelves alone more than triple our capacity to conduct daily experiments,\u201d said Henry, who is also principal investigator on the NIH COBRE grant <a href=\"https:\/\/umaine.edu\/news\/blog\/2023\/03\/30\/umaine-awarded-11-3-million-from-nih-to-support-biomedical-research\/\">awarded<\/a> to 91福利 in 2023. \u201cThat means more data, faster results and an overall boost in scientific productivity, not just for COBRE investigators, but for all faculty and students working with zebrafish.\u201d<\/p>\n\n\n\n<p>Mark Nilan, who has managed 91福利\u2019s zebrafish lab since its founding in 2003, played a critical role in the expansion\u2019s design and implementation.<\/p>\n\n\n\n<p>\u201cThis renovation is the most significant upgrade our facility has ever seen,\u201d Nilan said. \u201cIt dramatically improves the workflow for researchers, and it\u2019s gratifying to see how the infrastructure now reflects the excellence of the science happening here.\u201d<\/p>\n\n\n\n<p>A key advantage of the expanded space is the ability to rear zebrafish at lower densities, which speeds the time to sexual maturity from four to just two months.<\/p>\n\n\n\n<p>\u201cDedicated nursery tanks mean we\u2019re no longer limited in how quickly we can establish or expand transgenic lines,\u201d said Henry. \u201cThat\u2019s a huge deal for genetic and developmental research.\u201d<\/p>\n\n\n\n<p>The NIH COBRE-funded renovation also supports 91福利\u2019s collaborative research environment. When new faculty join the university, lab space and resources are often reallocated to support their work. With the expanded capacity, new researchers can integrate into the zebrafish research community without displacing existing projects.<\/p>\n\n\n\n<p>\u201cThis is about building a sustainable, forward-looking research infrastructure,\u201d said Henry. \u201cThe lab doesn\u2019t just support current faculty, it helps recruit and retain future scientists. It gives us room to grow.\u201d<\/p>\n\n\n\n<p>\u201cThis project reflects the university\u2019s long-term commitment to zebrafish-based research,\u201d Nilan said. \u201cWith these upgrades, we can support more investigators, offer world-class training to students and early-career faculty and accelerate biomedical solutions to long-standing health challenges.\u201d<\/p>\n\n\n\n<p>The newly expanded zebrafish laboratory is now fully operational. 91福利\u2019s Coordinated Operating Research Entities (CORE), which has managed the lab since 2018, offers additional information about the lab and other shared research resources <a href=\"https:\/\/umaine.edu\/core\/zebrafish\/\">online<\/a>.\u00a0<\/p>\n\n\n\n<p><strong>Contact: <\/strong>Erin Miller, erin.miller@maine.edu<\/p>\n","protected":false},"excerpt":{"rendered":"<p>91福利 unveiled an expanded and renovated zebrafish laboratory in Hitchner Hall this July. The facility, jointly funded by two grants from the National Institutes of Health (NIH) totaling $650,000 with additional investment by 91福利, significantly expands the university\u2019s capacity for biomedical research using zebrafish. Zebrafish have genomes and immune systems similar to [&hellip;]<\/p>\n","protected":false},"author":445,"featured_media":51287,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","spc_primary_category":65},"categories":[625,94,259,573,65],"tags":[],"class_list":["post-51283","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-arctic","category-impact-newsletter","category-umaine-medicine","category-program-highlight","category-research-news"],"featured_image_urls_v2":{"full":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129.jpg",1200,675,false],"thumbnail":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-150x150.jpg",150,150,true],"medium":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-300x169.jpg",300,169,true],"medium_large":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-768x432.jpg",768,432,true],"large":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-1024x576.jpg",1024,576,true],"1536x1536":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129.jpg",1200,675,false],"2048x2048":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129.jpg",1200,675,false],"archive_9_5":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-360x200.jpg",360,200,true],"portrait_3x4":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-105x59.jpg",105,59,true],"image_16_9":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-600x338.jpg",600,338,true],"image_15_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-600x280.jpg",600,280,true],"image_25_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-600x168.jpg",600,168,true],"3col-image_16_9":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-317x178.jpg",317,178,true],"3col-image_15_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-317x148.jpg",317,148,true],"3col-image_full":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-317x178.jpg",317,178,true],"4col-image_16_9":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-423x238.jpg",423,238,true],"4col-image_15_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-423x197.jpg",423,197,true],"4col-image_full":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-423x238.jpg",423,238,true],"6col-image_16_9":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-634x356.jpg",634,356,true],"6col-image_15_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-634x296.jpg",634,296,true],"6col-image_full":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-634x357.jpg",634,357,true],"8col-image_16_9":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-846x476.jpg",846,476,true],"8col-image_15_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-846x395.jpg",846,395,true],"8col-image_full":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-846x476.jpg",846,476,true],"9col-image_16_9":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-951x535.jpg",951,535,true],"9col-image_15_7":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-951x444.jpg",951,444,true],"9col-image_full":["https:\/\/umaine.edu\/research\/wp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unveiled an expanded and renovated zebrafish laboratory in Hitchner Hall this July. The facility, jointly funded by two grants from the National Institutes of Health (NIH) totaling $650,000 with additional investment by 91福利, significantly expands the university\u2019s capacity for biomedical research using zebrafish. Zebrafish have genomes and immune systems similar to humans, making them ideal models for studying genetic, developmental and toxicological variables. The paperclip-sized minnows are prolific and mature quickly. Their more unusual attributes, like having transparent skin as embryos, have made them mainstays in research labs for over a century. 91福利 is a well-established&hellip;<\/p>\n","category_list_v2":"<a href=\"https:\/\/umaine.edu\/research\/category\/arctic\/\" rel=\"category tag\">Arctic<\/a>, <a href=\"https:\/\/umaine.edu\/research\/category\/impact-newsletter\/\" rel=\"category tag\">IMPACT Newsletter<\/a>, <a href=\"https:\/\/umaine.edu\/research\/category\/umaine-medicine\/\" rel=\"category tag\">Medicine<\/a>, <a href=\"https:\/\/umaine.edu\/research\/category\/program-highlight\/\" rel=\"category tag\">Program Highlight<\/a>, <a href=\"https:\/\/umaine.edu\/research\/category\/research-news\/\" rel=\"category tag\">Research News<\/a>","author_info_v2":{"name":"emiller","url":"https:\/\/umaine.edu\/research\/author\/emiller\/"},"comments_num_v2":"0 comments","taxonomy_info":{"category":[{"value":625,"label":"Arctic"},{"value":94,"label":"IMPACT Newsletter"},{"value":259,"label":"Medicine"},{"value":573,"label":"Program Highlight"},{"value":65,"label":"Research News"}]},"featured_image_src_large":["https:\/\/umaine.edu\/research\/wp-content\/uploads\/sites\/281\/2025\/09\/2025-9-zebrafish-121422_AK_DSC01129-1024x576.jpg",1024,576,true],"author_info":{"display_name":"emiller","author_link":"https:\/\/umaine.edu\/research\/author\/emiller\/"},"comment_info":0,"category_info":[{"term_id":625,"name":"Arctic","slug":"arctic","term_group":0,"term_taxonomy_id":625,"taxonomy":"category","description":"","parent":0,"count":3,"filter":"raw","cat_ID":625,"category_count":3,"category_description":"","cat_name":"Arctic","category_nicename":"arctic","category_parent":0},{"term_id":94,"name":"IMPACT Newsletter","slug":"impact-newsletter","term_group":0,"term_taxonomy_id":94,"taxonomy":"category","description":"","parent":0,"count":112,"filter":"raw","cat_ID":94,"category_count":112,"category_description":"","cat_name":"IMPACT Newsletter","category_nicename":"impact-newsletter","category_parent":0},{"term_id":259,"name":"Medicine","slug":"umaine-medicine","term_group":0,"term_taxonomy_id":259,"taxonomy":"category","description":"","parent":0,"count":21,"filter":"raw","cat_ID":259,"category_count":21,"category_description":"","cat_name":"Medicine","category_nicename":"umaine-medicine","category_parent":0},{"term_id":573,"name":"Program Highlight","slug":"program-highlight","term_group":0,"term_taxonomy_id":573,"taxonomy":"category","description":"","parent":0,"count":41,"filter":"raw","cat_ID":573,"category_count":41,"category_description":"","cat_name":"Program Highlight","category_nicename":"program-highlight","category_parent":0},{"term_id":65,"name":"Research News","slug":"research-news","term_group":0,"term_taxonomy_id":65,"taxonomy":"category","description":"","parent":0,"count":226,"filter":"raw","cat_ID":65,"category_count":226,"category_description":"","cat_name":"Research News","category_nicename":"research-news","category_parent":0}],"tag_info":false,"_links":{"self":[{"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/posts\/51283","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/users\/445"}],"replies":[{"embeddable":true,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/comments?post=51283"}],"version-history":[{"count":5,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/posts\/51283\/revisions"}],"predecessor-version":[{"id":51297,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/posts\/51283\/revisions\/51297"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/media\/51287"}],"wp:attachment":[{"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/media?parent=51283"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/categories?post=51283"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/umaine.edu\/research\/wp-json\/wp\/v2\/tags?post=51283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}