This new guidance goes hand in hand with a previously shared NIH notice, NOT-OD-25-132, which describes potential research misconduct risks of using AI in generating research applications.

All NIH researchers are encouraged to review this article. It may also provide helpful context for other researchers, as more funding agencies will likely release their own AI guidance in the future.

For more information on AI at 91����, please see the .

For more information on research misconduct, please see the Office of Research Compliance’s Research Misconduct website.

This NIH notice decisively limits the use of AI in research applications and describes potential research misconduct risks of using AI:

“Researchers should be aware that using AI comes with its own risks. AI use may result in plagiarism, fabricated citations, or other kinds of research misconduct.”

Beyond this, NIH also states:

“If the detection of AI is identified post award, NIH may refer the matter to the Office of Research Integrity to determine whether there is research misconduct ��…].”

The is the federal agency that oversees research misconduct inquiries and investigations for any institutions that receive U.S. Public Health Service (PHS) funding – such as the University of Maine.

Lastly, the NIH notice also has implications for grants and submission limits. Please see the Office of Research Administration (ORA) for further guidance on that topic.

For more information on AI at 91����, please see the .

For more information on research misconduct, please see the Office of Research Compliance’s Research Misconduct website.

This NIH guidance provides “policies, best practices, and regulations,” specifically addressing the following topics:

• Research Participant Protections
• Data Management and Sharing
• Health Information Privacy
• Licensing, Intellectual Property, & Technology Transfer
• Peer Review
• Biosecurity and Biosafety

The Office of Research Compliance recommends this resource to researchers involved in the use of AI in research, particularly those conducting NIH-supported research.