Emily Spaulding, Ph.D., The George Wojtech Endowed Chair in Neurobiology at MDIBL and a “pipeline junior faculty” in the COBRE grant team will present on June 23.<\/p>\n
What drives neurodegenerative diseases like amyotrophic lateral sclerosis (ALS)?<\/strong><\/p>\n Dr. Spaulding will discuss how her lab leverages the advantages of a transparent roundworm to better understand the contribution of disrupted cell organization to neurodegenerative conditions like ALS.<\/p>\n Want to learn more about the animal models that make this research possible? Register now<\/a> to join us Monday, June 23, 2025 at 5 p.m. The Spaulding Lab uses the optically clear nematode, C. elegans<\/em>, which contain 302 well-characterized neurons, all of which are visible in an intact, living animal. The researchers combine CRISPR\/Cas9-genetic engineering of neurodegenerative disease-associated genes with super-resolution imaging of living, adult worms to understand how disrupted cell organization leads to neuronal dysfunction.<\/p>\n The Lab\u2019s goal is to uncover new therapeutic targets to treat neurodegenerative disease.<\/p>\n The MDI Science Caf\u00e9 Series is brought to you by Cross Insurance<\/p>\n <\/p>\n","protected":false},"excerpt":{"rendered":" Emily Spaulding, Ph.D., The George Wojtech Endowed Chair in Neurobiology at MDIBL and a “pipeline junior faculty” in the COBRE grant team will present on June 23. 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\nWatch this reel on C. elegans<\/em>!<\/a><\/p>\n
\nin Maren Auditorium (#4 on map)<\/a> or via Zoom<\/em>.<\/em><\/p>\n