BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Center for Biomedical Research Excellence (COBRE) - ECPv6.15.17.1//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:/cobre X-WR-CALDESC:Events for Center for Biomedical Research Excellence (COBRE) REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20240310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20241103T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20250309T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20251102T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20260308T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20261101T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20270314T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20271107T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;VALUE=DATE:20251023 DTEND;VALUE=DATE:20251025 DTSTAMP:20260607T133910 CREATED:20250905T125044Z LAST-MODIFIED:20250905T125044Z UID:10000027-1761177600-1761350399@umaine.edu SUMMARY:2025 91¸ŁŔű COBRE Retreat DESCRIPTION:The third 91¸ŁŔű COBRE Retreat will take place October 23-25\, 2025\, at the MDI Biological Laboratory in Bar Harbor\, Maine. This invite-only event gathers senior personnel\, project and core leaders\, mentors\, and advisory committee members for research updates\, group discussions\, and individualized feedback from the External Advisory Committee. Travel\, meals\, and accommodations will be provided. \n  URL:/cobre/event/2025-umaine-cobre-retreat/ LOCATION:MDI Biological Laboratory\, 159 Old Bar Harbor Rd\, Bar Harbor\, ME CATEGORIES:Event,News,Research ATTACH;FMTTYPE=image/jpeg:/cobre/wp-content/uploads/sites/681/2025/09/mdibl-signage-e1757076589283.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20251106T150000 DTEND;TZID=America/New_York:20251106T160000 DTSTAMP:20260607T133910 CREATED:20251009T163303Z LAST-MODIFIED:20251016T192845Z UID:10000039-1762441200-1762444800@umaine.edu SUMMARY:Making and Breaking the Barrier: Development of the Diaphragm and Congenital Diaphragmatic Hernias DESCRIPTION:Seminar Topic: \nThe diaphragm is an essential mammalian skeletal muscle\, as it is vital for respiration and serves as a barrier between the thoracic and abdominal cavities. Defects in diaphragm development are the cause of congenital diaphragmatic hernia (CDH) a common birth defect (1 in 3000 births) that results in severe morbidity and 50% mortality. Development of the diaphragm requires the integration of multiple tissues that derive from several embryonic sources. I will describe our recent research on the critical role of the connective tissue in guiding normal diaphragm development and how defects in the connective tissue are the cause of CDH. \nBiography: \nDr. Gabrielle Kardon is a professor at the University of Utah whose lab studies skeletal muscle development\, regeneration\, response to viral infection\, and evolution. Always interested in evolution\, she initially studied geology and paleontology at Yale University and then at the University of Michigan. After learning about the role of Hox genes in regulating development and evolution\, she switched her research focus to developmental biology. At Duke University\, with mentorship from David McClay and Stephen Wainwright\, she completed her PhD on the development of limb muscle and tendons. She did postdoctoral training with Cliff Tabin at Harvard Medical School\, where she began investigating the role of interactions between muscle and muscle connective tissue fibroblasts in the development of limb muscle. Since 2004\, she has had an independent lab at the University of Utah. Her lab currently concentrates on three areas of research. The lab studies the development of the diaphragm\, the genetic and cellular causes of the common birth defect\, Congenital Diaphragmatic Hernias\, and the evolutionary origin of this critical mammalian muscle. The lab also investigates the cellular and molecular processes regulating adult muscle regeneration after acute\, sterile injury. Finally\, her lab has been investigating how infection by mosquito-borne alphaviruses  – a major and growing health concern – causes acute and chronic muscle weakness. \nPlease visit HERE for more information on her lab. \nThis event is in-person in Nutting Hall Room 257 on November 6th at 3:00 PM \nA virtual option is also available.  Please register if you plan to attend virtually. URL:/cobre/event/cobre-kardon-seminar/ LOCATION:Nutting 257\, 04469 CATEGORIES:Education,Event ATTACH;FMTTYPE=image/png:/cobre/wp-content/uploads/sites/681/2025/10/IoM-Seminar-Template-1-1.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20260403T150000 DTEND;TZID=America/New_York:20260403T163000 DTSTAMP:20260607T133910 CREATED:20260331T180058Z LAST-MODIFIED:20260331T180058Z UID:10000040-1775228400-1775233800@umaine.edu SUMMARY:Exploring tissue-specific mechanisms and requirements for nucleolar organization using C. elegans DESCRIPTION:The School of Biology and Ecology presents: \nExploring tissue-specific mechanisms and requirements for nucleolar organization using C. elegans \nSpeaker:  Dr. Emily Spaulding Assistant Professor and The George Wojtech Endowed Chair in Neurobiology at MDI Biological Lab \nFriday\, April 3\, 3pm Norman Smith 107 \nRefreshments served! \nDisruptions in the organization of neurons contributes to neurodegeneration\, including Alzheimer’s disease\, Parkinson’s disease\, and ALS. However\, studying neuronal organization in mammals is technically challenging because neurons are buried deep inside the animal. To overcome this challenge\, the Spaulding Lab uses the optically clear nematode\, C.elegans\, which contains 302 well characterized neurons that are visible in an intact\, living animal. Her lab combines genetic engineering of neurodegenerative disease-associated genes with super-resolution imaging of living\, adult worms to understand how disrupted cell organization leads to neuronal dysfunction. Their goal is to uncover new therapeutic targets to treat neurodegenerative disease. URL:/cobre/event/exploring-tissue-specific-mechanisms-and-requirements-for-nucleolar-organization-using-c-elegans/ LOCATION:Norman Smith Hall 107 ATTACH;FMTTYPE=image/png:/cobre/wp-content/uploads/sites/681/2026/03/SpauldingSeminarPoster-scaled-e1774979777360.png END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20260614 DTEND;VALUE=DATE:20260618 DTSTAMP:20260607T133910 CREATED:20260521T150936Z LAST-MODIFIED:20260521T150936Z UID:10000041-1781395200-1781740799@umaine.edu SUMMARY:10th National IDeA Symposium of Biomedical Research Excellence (NISBRE) DESCRIPTION:Clarissa Henry\, PhD\, PI for the COBRE grant and Cecile Ferguson\, program manager will attend the  the 10th Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE)\, held in person at the Bethesda North Marriott Hotel and Conference Center in Rockville\, Maryland\, from June 14–17\, 2026. This national conference is a premier event showcasing the scientific and training achievements of the National Institute of General Medical Sciences (NIGMS) IDeA program. The IDeA program supports centers of excellence and trains biomedical scientists in IDeA-eligible states. URL:/cobre/event/10th-national-idea-symposium-of-biomedical-research-excellence-nisbre/ LOCATION:Bethesda North Marriott Hotel and Conference\, Bethesda North Marriott Hotel and Conference Center\, Rockville\, MD ATTACH;FMTTYPE=image/jpeg:/cobre/wp-content/uploads/sites/681/2026/05/unnamed.jpg END:VEVENT END:VCALENDAR