{"id":818,"date":"2014-06-19T13:57:33","date_gmt":"2014-06-19T18:57:33","guid":{"rendered":"http:\/\/sites.umaine.edu\/newbiomed\/?page_id=818"},"modified":"2025-10-09T12:26:05","modified_gmt":"2025-10-09T16:26:05","slug":"melissa-maginnis","status":"publish","type":"page","link":"https:\/\/umaine.edu\/biomed\/home\/faculty\/melissa-maginnis\/","title":{"rendered":"Melissa Maginnis, Ph.D."},"content":{"rendered":"<style>.kb-image818_57e299-98 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<div class=\"wp-block-kadence-image kb-image818_57e299-98 is-style-default\"><figure class=\"alignright size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"300\" src=\"https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-200x300.jpg\" alt=\"\" class=\"kb-img wp-image-3051\" srcset=\"https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-200x300.jpg 200w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-683x1024.jpg 683w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-768x1152.jpg 768w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-1024x1536.jpg 1024w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-1365x2048.jpg 1365w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-93x140.jpg 93w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-317x475.jpg 317w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-423x634.jpg 423w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-634x951.jpg 634w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-846x1269.jpg 846w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-951x1426.jpg 951w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-1268x1902.jpg 1268w, https:\/\/umaine.edu\/biomed\/wp-content\/uploads\/sites\/651\/2025\/10\/Maginnis-headshot-scaled.jpg 1707w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,200px\" \/><figcaption>Melissa Maginnis, Associate Professor of Microbiology, 2025 Presidential Award Winner<\/figcaption><\/figure><\/div>\n\n\n\n<p class=\"has-text-align-left\"><strong>Associate Professor of Microbiology<br><\/strong><\/p>\n\n\n\n<p><strong>Maginnis<\/strong> <strong>Lab<br><\/strong>Hitchner Hall<br>Laboratory: Room 320<br>Laboratory Phone: (207) 581-2800<br>Office: Room 326 (interior to lab)<br>Office Phone: <a href=\"tel:207.581.2806\">207.581.2806<\/a><br>Email: <span style=\"color: #000000\"><a href=\"mailto:melissa.maginnis@maine.edu\">melissa.maginnis@maine.edu<br><\/a><\/span><span style=\"color: #000000\">L<\/span>ab website:&nbsp;<a title=\"Maginnis Lab\" href=\"http:\/\/umaine.edu\/maginnislab\/\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/umaine.edu\/maginnislab\/<\/a><\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>Education:<\/strong><br>B.S. (2001) Neumann College<br>Ph.D. (2007) Vanderbilt University<br>Postdoctoral Training: Brown University<\/p>\n\n\n\n<p><b>Teaching:<\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400\">The excitement and enthusiasm of my students motivates me to be a thoughtful and creative instructor. My teaching is focused on big picture concepts and development of skills that will prepare students for the next steps in their professional journey. I actively engage students in course work that is fun and rewarding by incorporating a variety of active-learning strategies so that students at different levels of learning and with different learning styles are actively engaged in class. I aim to keep my courses fresh and exciting by complementing my lectures with small group projects, student-led presentations, discussions of primary literature, book discussions, video discussions with experts in the fields, and the incorporation of podcast discussions. With varied types of assignments, my goal is to foster a love for learning and allow all students the opportunity to shine!<\/span><\/p>\n\n\n\n<p><b>Courses taught:<\/b><span style=\"font-weight: 400\">&nbsp; Phage Genome Discovery I (part of the HHMI, SEAPHAGES program), a research-intensive laboratory for first-year students; an undergraduate Virology course (BMB455); an undergraduate Virus-Cell Interactions Laboratory (BMB475); a graduate Virology course (BMB598); and undergraduate and graduate Seminar in Molecular and Biomedical Sciences (BMB480, 490, and 580). I also mentor students in independent research in my laboratory through Independent Study (BMB497), Capstone Research (BMB491), Honors Thesis Research (HON498\/499), and Graduate Thesis Research (BMB699).<\/span><\/p>\n\n\n\n<p><b>Research Interests:<\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400\">Research in the Maginnis laboratory is focused on understanding the cellular and molecular basis of viral disease. Specifically, our work seeks to define the viral and host cell factors that regulate infection and viral pathogenesis of the human JC polyomavirus (JCPyV). The majority of the population is infected with JCPyV, which establishes a lifelong, persistent infection in the kidney without symptoms. In immunocompromised hosts, such as individuals receiving immunomodulatory therapies for autoimmune diseases or those with HIV, the virus can spread from the kidney to the central nervous system and cause a lytic infection in the brain. Viral destruction of the glial cells astrocytes and oligodendrocytes, which are critical for myelin production, results in the fatal, demyelinating disease progressive multifocal leukoencephalopathy (PML). There is currently no effective treatment for PML.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400\">Viruses are complex, yet extremely efficient machines that hijack the host cell machinery to complete an infectious cycle and produce progeny virus. The interplay between JCPyV and host cell factors is critical to understanding disease outcomes and PML pathogenesis. Research in my laboratory is focused on understanding the detailed molecular interactions between the virus and host cell factors that drive the early steps in the infectious cycle including entry, trafficking, and viral transcription. In particular, we are focused on defining how JCPyV uses the serotonin receptor to transverse the plasma membrane, identifying signaling cascades that drive viral transcription, and elucidating how the virus causes persistent and lytic infections in specific cell types. This research will allow us to define key unanswered questions in JCPyV biology, provide crucial insights into JCPyV pathogenesis, and identify novel targets for rational drug design for prevention and treatment of PML.<\/span><\/p>\n\n\n\n<p><strong>Education-Related Publications <\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Maginnis, M.S. <\/strong>(2025) The Future of Virology Education. <em>Annual Reviews in Virology<\/em>, <em>Vol. 12:43-57<\/em>.<br><\/li>\n\n\n\n<li><strong>*<\/strong>Kushner, D.B., Cline, T.D., Danthi, P., Debbink, K.M., Ferran, M.C., Flenniken, M., Johnson, D.M., Mehle, A., Morales, D.A., Mukhopadhyay, S., Parker, J.S.L., Spriggs, C.C., <strong>*<\/strong>O&#8217;Donnell, L.A., and <strong>*Maginnis, M.S. <\/strong>(2022) Curriculum Guidelines for Graduate and Undergraduate Virology Courses. <em>Journal of Virology,<\/em> <em>96(18):e01305-22<\/em>. <strong>*, Co-corresponding authors.<\/strong><\/li>\n<\/ul>\n\n\n\n<p><strong>Teaching-Related Publications<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ashby, S. Bressette, G., Brown, S., Charles, S., <strong>Maginnis, M.<\/strong>, Molloy, S.D., and Neely, M.N. (2022). Genome Sequence of Singleton <em>Gordonia terrae<\/em> Bacteriophage Finkle. <em>Microbiology Resource Announcements, Bacteriophages<\/em>, 11(9):e0069322.<\/li>\n\n\n\n<li>Curtis, B., Ganbaatar, B., Lawrence, G., Oglesby, W., Rice, J., Tremblay, E., <strong>Maginnis, M.<\/strong>, Molloy, S.D., and Neely, M.N. (2022). Genome Sequence of the Cluster CD Gordonia Phage Widow. <em>Microbiology Resource Announcements, Bacteriophages<\/em>,11(10):e0069522.<\/li>\n<\/ul>\n\n\n\n<p><b><br>Research Publications:&nbsp;<\/b><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pike, A.M.C., Amal, S., <strong>Maginnis, M.S.<\/strong>, and Wilczek, M.P. (2025). Evaluating Neural Network Performance in Predicting Disease Status and Tissue Source of JC Polyomavirus from Patient Isolates Based on the Hypervariable Region of the Viral Genome. <em>Viruses<\/em>,&nbsp;<em>17<\/em>(1), 12.<\/li>\n\n\n\n<li>Obeng, B., Bennett, L.J., West, B.E., Wagner, D.J., Fleming, P.J., Tasker, M.N., Lorenger, M.K., Smith, D.R., Systuk, T., Plummer, S.M., Eom, J., Paine, M.D., Frangos, C.T., Wilczek, M.P., Shim, J.K., <strong>Maginnis, M.S.<\/strong>, and Gosse, J.A. (2024) Antimicrobial Cetylpyridinium Chloride Suppresses Mast Cell Function by Targeting Tyrosine Phosphorylation of Syk Kinase. <em>Journal of Immunotoxicology<\/em>, 21(1):2443397.<\/li>\n\n\n\n<li>Sandberg, A.L., Bond, A.C.S., Bennett, L.J., Craig, S.E., Kirkby, L.C., Kraemer, A.R.,&nbsp;Kelly, K.G.,and <strong>Maginnis, M.S.<sup> +<\/sup><\/strong> (2024). GPCR Inhibitors Have Antiviral Properties against JC Polyomavirus Infection.&nbsp;<em>Viruses<\/em>, 16(10): 1559.<strong><sup> +<\/sup><em>, Corresponding author.<\/em><\/strong><\/li>\n\n\n\n<li>Bond, A.C.S., Crocker, M.A., Wilczek, M.P., DuShane, J.K., Sandberg, A.L., Bennett, L.J., Leclerc, N.R., and <strong>Maginnis, M.S.<\/strong><strong><sup> +<\/sup><\/strong> (2024). High-throughput Drug Screen Identifies Calcium and Calmodulin Inhibitors that Reduce JCPyV Infection. <em>Antiviral Research<\/em>, 222: 105817.<strong><sup> +<\/sup><em>, Corresponding author.<\/em><\/strong><\/li>\n\n\n\n<li><b>Maginnis, M.S. <strong><sup>+<\/sup><\/strong><\/b><b> <\/b><span style=\"font-weight: 400\">(2023). <\/span><span style=\"font-weight: 400\">Beta<\/span><span style=\"font-weight: 400\">-arrestin and G protein-coupled Receptor Kinases in Viral Entry: A graphical review. <\/span><i><span style=\"font-weight: 400\">Cellular Signaling<\/span><\/i><span style=\"font-weight: 400\">, 102: 110558. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">&nbsp;Mehmood, K., Wilczek, M.P., DuShane, J.K., Parent, M.T., Mayberry, C.L., Wallace, J.N., Levasseur, F.L., Fong, T.M., Hess, S.T.<\/span><b>+<\/b><span style=\"font-weight: 400\">, and <\/span><b>Maginnis, M.S.<\/b><b> +<\/b><span style=\"font-weight: 400\"> (2022). Dynamics and Patterning of 5-Hydroxytryptamine 2 Subtype Receptors in Response to Ligand JC Polyomavirus. <\/span><i><span style=\"font-weight: 400\">Viruses<\/span><\/i><span style=\"font-weight: 400\">, 14(12), 2597. <\/span><b>+<\/b><b><i>, Corresponding author. <\/i><\/b><b>[Selected as Highlight Paper].<\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Regan, D., Fong, C., Bond, A.C.S., Desjardins, C., Hardcastle, J., Hung, S.H., Holmes, A.P., Schiffman, J.D., <\/span><b>Maginnis, M.S.<\/b><span style=\"font-weight: 400\">, and Howell, C. (2022). Improved Recovery of Captured Airborne Bacteria and Viruses with Liquid-coated Air Filters. <\/span><i><span style=\"font-weight: 400\">ACS Applied Materials &amp; Interfaces<\/span><\/i><span style=\"font-weight: 400\">, 14(45):50543-50556.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Wilczek, M.P., Pike, A.C., Craig, S., <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><b>,<\/b><span style=\"font-weight: 400\"> and King, B.L.<\/span><b> + <\/b><span style=\"font-weight: 400\">(2022) Rearrangement in the Hypervariable Region of JC Polyomavirus Genomes Isolated from Patient Samples and Impact on Transcription Factor-Binding Sites and Disease Outcomes. <\/span><i><span style=\"font-weight: 400\">IMJS<\/span><\/i><span style=\"font-weight: 400\">, <\/span><i><span style=\"font-weight: 400\">23<\/span><\/i><span style=\"font-weight: 400\">(10), 5699. <\/span><b>+<\/b><b><i>, Corresponding authors.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Wilczek, M.P., Armstrong, F.A., Mayberry, C.L., King, B.L. and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2021). PI3K\/AKT\/mTOR Signaling Pathway is Required for JCPyV Infection in Primary Astrocytes. <\/span><i><span style=\"font-weight: 400\">Cells<\/span><\/i><span style=\"font-weight: 400\">, 10(11), 3218. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Wilczek, M.P., Armstrong, F.J., Geohegan, R.P., Mayberry, C.L., DuShane, J.K., King, B.L., and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2021). The MAPK\/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes. <\/span><i><span style=\"font-weight: 400\">Viruses<\/span><\/i><span style=\"font-weight: 400\">, 13:1834. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Mayberry, C.L., Bond, C.S., Wilczek, M.P., Mehmood, K., and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2021). Sending Mixed Signals: Polyomavirus Entry and Trafficking. <\/span><i><span style=\"font-weight: 400\">Current Opinion in Virology<\/span><\/i><span style=\"font-weight: 400\">, 47:95-105. <\/span><b>[Invited review]. <\/b><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Mayberry, C.L., Wilczek, M.P., Fong, T.M., Nichols, S.L., and <\/span><b>Maginnis, M.S.+ <\/b><span style=\"font-weight: 400\">(2021). GRK2 Mediates b-arrestin Interactions with 5-HT<\/span><span style=\"font-weight: 400\">2<\/span><span style=\"font-weight: 400\"> Receptors for JC Polyomavirus Endocytosis. <\/span><i><span style=\"font-weight: 400\">Journal of Virology; <\/span><\/i><span style=\"font-weight: 400\">95(7):e02139-20. <\/span><b>[Spotlight Article]. <\/b><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Mayberry, C.L. and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\">(2020). Taking the Scenic Route: polyomaviruses utilize multiple pathways to reach the same destination. <\/span><i><span style=\"font-weight: 400\">Viruses, <\/span><\/i><span style=\"font-weight: 400\">12(10):1168. <\/span><b>[Invited Review]. <\/b><b><i>+<\/i><\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Wilczek, M.P., DuShane, J.K., Armstrong, F.A., and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2020). JC Polyomavirus Infection Reveals Delayed Progression of the Infectious Cycle in Normal Human Astrocytes. <\/span><i><span style=\"font-weight: 400\">Journal of Virology<\/span><\/i><span style=\"font-weight: 400\">, 94(5): e01331-19. <\/span><b>[Cover Illustration]<\/b><span style=\"font-weight: 400\">. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">DuShane, J.K., Mayberry, C.L., Wilczek, M.P., Nichols, S.L., and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2019). JCPyV-Induced MAPK Signaling Activates Transcription Factors during Infection. <\/span><i><span style=\"font-weight: 400\">International Journal of Molecular Sciences<\/span><\/i><span style=\"font-weight: 400\">, 20(19):4779.<\/span><b> +<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">DuShane, J.K. and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2019). DNA Virus Exploitation of the MAPK-ERK Cascade. <\/span><i><span style=\"font-weight: 400\">International Journal of Molecular Sciences<\/span><\/i><span style=\"font-weight: 400\">, 20(14):3427.<\/span><b> [Invited Review]. <\/b><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Assetta, B., Morris-Love, J., Gee, G.V., Atkinson, A., O\u2019Hara, B.A., <\/span><b>Maginnis, M.S.<\/b><span style=\"font-weight: 400\">, Haley, S.A., and Atwood, W.J. (2019). Genetic and Functional Dissection of the Role of Individual 5-HT<\/span><span style=\"font-weight: 400\">2<\/span><span style=\"font-weight: 400\"> Receptors as Entry Receptors for JC Polyomavirus. <\/span><i><span style=\"font-weight: 400\">Cell Reports<\/span><\/i><span style=\"font-weight: 400\">, 27(7):1960-1966.e6.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">DuShane, J.K., Wilczek, M.P., Crocker, M.A., <\/span><b>Maginnis, M.S.<\/b><b>+ <\/b><span style=\"font-weight: 400\">(2019). High-Throughput Characterization of Viral and Cellular Protein Expression Patterns during JC Polyomavirus Infection. <\/span><i><span style=\"font-weight: 400\">Frontiers in Microbiology<\/span><\/i><span style=\"font-weight: 400\">, 10:783. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Curthoys, N.M., Mlodzianoski, M.J., Parent, M., Butler, M.B., Raut, P., Wallace, J., Lilieholm, J., Mehmood, K., <\/span><b>Maginnis, M.S.<\/b><span style=\"font-weight: 400\">, Waters, H., Busse, B., Zimmerberg, J., and Hess ST. (2019). Influenza Hemagglutinin Modulates Phosphatidylinositol 4,5-Bisphosphate Membrane Clustering. <\/span><i><span style=\"font-weight: 400\">Biophysical Journal<\/span><\/i><span style=\"font-weight: 400\">, 116(5):893-909.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Mayberry, C.L., Soucy, A.N., Lajoie, C.R., DuShane, J.K., and <\/span><b>Maginnis, M.S.<\/b><b>+ <\/b><span style=\"font-weight: 400\">(2019). JC Polyomavirus Entry by Clathrin-Mediated Endocytosis is Driven by \u03b2-arrestin. <\/span><i><span style=\"font-weight: 400\">Journal of Virology<\/span><\/i><span style=\"font-weight: 400\">, 93(8):e01948-18. <\/span><b>[Spotlight Article]<\/b><span style=\"font-weight: 400\">. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><b>Maginnis, M.S.<\/b><b>+<\/b> <span style=\"font-weight: 400\">(2018). Virus-Receptor Interactions: The Key to Cellular Invasion. <\/span><i><span style=\"font-weight: 400\">Journal of Molecular Biology<\/span><\/i><span style=\"font-weight: 400\">, 430(17):2590-2611. <\/span><b>[Invited Review].<\/b><b><i> +<\/i><\/b><b><i>,Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">DuShane, J.K., Wilczek, M.P., Mayberry, C.L., and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b><span style=\"font-weight: 400\"> (2018). ERK is a Critical Regulator of JCPyV Infection. <\/span><i><span style=\"font-weight: 400\">Journal of Virology<\/span><\/i><span style=\"font-weight: 400\">, 92(7):e01529-17. <\/span><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Mayberry, C.L., Nelson, C.D.S., and <\/span><b>Maginnis, M.S.<\/b><b>+<\/b> <span style=\"font-weight: 400\">(2017). JC Polyomavirus Attachment and Entry: Potential Sites for PML Therapeutics. <\/span><i><span style=\"font-weight: 400\">Current Clinical Microbiology Reports<\/span><\/i><span style=\"font-weight: 400\">, 4(3):132-141. <\/span><b>[Invited Review]. <\/b><b>+<\/b><b><i>, Corresponding author.<\/i><\/b><\/li>\n\n\n\n<li><span style=\"font-weight: 400\">Dimitriadi, M., Derdowski, A., Kalloo, G., <\/span><b>Maginnis, M.S.<\/b><span style=\"font-weight: 400\">, Bliska, B., O\u2019 Hern, P., Nguyen, K.C.Q., Cook, S.J., Poulogiannis, G., Atwood, W.J., Hall, D.H., and Hart, A.C. (2016). Decreased Function of Survival Motor Neuron Protein Impairs Endocytic Pathways. <\/span><i><span style=\"font-weight: 400\">PNAS<\/span><\/i><span style=\"font-weight: 400\">, 113(30):E4377-86.<\/span><\/li>\n\n\n\n<li>Str\u00f6h, L.J.*, <b>Maginnis, M.S.*<\/b>, Blaum, B.S., Nelson, C.D., Neu, U., Gee, G.V., O\u2019Hara, B.A., Motamedi, N., DiMaio, D., Atwood, W.J., and Stehle, T. (2015). The Greater Affinity of JC Polyomavirus Capsid for \u03b12,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. <i>Journal of Virology, <\/i>89(12):6364-75.<i>*<\/i><b>, Denotes equal contribution.<\/b><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Associate Professor of Microbiology Maginnis LabHitchner HallLaboratory: Room 320Laboratory Phone: (207) 581-2800Office: Room 326 (interior to lab)Office Phone: 207.581.2806Email: melissa.maginnis@maine.eduLab website:&nbsp;http:\/\/umaine.edu\/maginnislab\/ Education:B.S. (2001) Neumann CollegePh.D. (2007) Vanderbilt UniversityPostdoctoral Training: Brown University Teaching: The excitement and enthusiasm of my students motivates me to be a thoughtful and creative instructor. My teaching is focused on big picture [&hellip;]<\/p>\n","protected":false},"author":927,"featured_media":3047,"parent":75,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"templates\/page-withsidebar.php","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-818","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Melissa Maginnis, Ph.D. - Molecular &amp; Biomedical Sciences - University of Maine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/umaine.edu\/biomed\/home\/faculty\/melissa-maginnis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melissa Maginnis, Ph.D. - Molecular &amp; Biomedical Sciences - University of Maine\" \/>\n<meta property=\"og:description\" content=\"Associate Professor of Microbiology Maginnis LabHitchner HallLaboratory: Room 320Laboratory Phone: (207) 581-2800Office: Room 326 (interior to lab)Office Phone: 207.581.2806Email: melissa.maginnis@maine.eduLab website:&nbsp;http:\/\/umaine.edu\/maginnislab\/ Education:B.S. 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